Its main use is in the treatment of excessive menstrual flow , either during the period its self menorrhogia or with blood loss between periods memorrhagia. In addition to its antithermorrhaging qualities, periwinkle has been named as an astringent, as a remedy for "nervous disorder" and as a treatment for high blood pressure. Its antrigency makes it a useful mouth wash for sore throats, gingivitis and canker sores. Also used digestive problem such as colitis or diarrhea where it will act to reduce the loss fluid or blood whilst toning the membrance.
Since vincamine was discovered in the leaves, Periwinkle has been used to treat arteriosclerosisand for dementia due to insufficient blood flow to brain. it contain vincamine, precursor chemicalvinpocetine, in its leaves and seeds. There is some clinical evidence that the periwinkle chemical vinpocetine can increase blood flow to the brain, increasing oxygination and also protect brain cell from damage by a chemical called phosphodiesterase. Vipocetine is also commended for memory enhancement in health people. and tried as a means of reducing brain injury after strokes.
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